Фундаментальные и прикладные аспекты иммунологии, генетики и инфектологии

Сборник научных статей участников Международной научно-практической конференции
г. Уфа, 13-14 ноября 2020 г.

INNOVATIVE TREATMENT IN COMPLEX THERAPY OF TYPE 1 DIABETES MELLITUS (DM 1) BY FREE IMPLANTATION OF ISLET CULTURES

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Aripova T.U.
Institute of Immunology and human genomics of Academy of Science of the Republic of Uzbekistan, Uzbekistan
Aripova N.U.
Institute of Immunology and human genomics of Academy of Science of the Republic of Uzbekistan, Uzbekistan
Ashurova F.Q.
Institute of Immunology and human genomics of Academy of Science of the Republic of Uzbekistan, Uzbekistan
Ruzimurodov N.F.
Institute of Immunology and human genomics of Academy of Science of the Republic of Uzbekistan, Uzbekistan
Nazirkulov O.M.
Institute of Immunology and human genomics of Academy of Science of the Republic of Uzbekistan, Uzbekistan
Currently, the only possible way to cure patients with diabetes is transplantation of the pancreas or its cells, which is a very effective way to achieve and maintain long-term physiological control of blood glucose, but due to various risks (rejection) associated with surgical interventions, this method is rarely used. We experimentally developed an effective method for the surgical treatment of diabetes mellitus by free implantation of pancreatic cell cultures and introduced into clinical practice. We have proved for the first time that xenografts for patients with type 1 diabetes mellitus in 50% of cases reduce the need for insulin in the first year after surgery.
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